COVID-19 Vaccine Booster Dose for Omicron Variant

COVID-19 Vaccine Booster Dose for Omicron Variant: COVID-19 Omicron Variant Vaccine Booster Dose: Britain’s Health Protection Agency (UKHSA) said on Friday that the third booster dose of the Covid-19 vaccine provides 70-75 percent protection against symptomatic infection of the Omicron variant. In its latest technical briefing, the agency said both dosages of Oxford/AstraZeneca’s Covishield and Pfizer/BioNTech vaccines currently provide “very low levels” of protection against symptomatic infections compared to the dominant delta variants.

However, based on analysis of data from 581 Omicron cases, a third top-up dose boosts immunity against the new variant. UKHSA said that it has been estimated that by the end of this month the number of infected in the UK will cross one million if the current trend does not change. Preliminary data showed that effectiveness against the new variant increases significantly in the initial period after a booster dose, providing approximately 70–75 percent protection against symptomatic infections.

The figures may also vary due to the preliminary nature of the findings. Health experts have reiterated that vaccination still has the potential to provide better protection against severe covid, which require hospital treatment. Dr Mary Ramsay, head of vaccination at UKHSA, said these early estimates should be considered with caution, but they indicate that a few months after the second wave, there is a higher risk of Omicron variants than Delta.

COVID-19 Vaccine Booster Dose for Omicron Variant

COVID-19 Vaccine Booster Dose for Omicron Variant
COVID-19 Vaccine Booster Dose for Omicron Variant

We expect the vaccines to show high protection against serious complications of COVID-19, so if you haven’t taken your first two doses yet, please book an appointment right away. He emphasized things like working from home if possible, wearing masks continuously in crowded or enclosed places, washing your hands regularly, staying in isolation and getting tested.

108 countries recognized India’s Covid-19 Vaccine Certificate

The government said in the Lok Sabha on Friday that a total of 108 countries have recognized India’s certificate related to anti-covid vaccination. This information was given by the Union Minister of State for Health, Bharti Pawar in a written reply to a question in the Lok Sabha. He said the World Health Organization’s ‘List for Emergency Use’ (EUL) assists procurement agencies and countries in recognizing the acceptability of use of various vaccines.

The minister said that a total of 108 countries have recognized India’s certificate related to anti-corona vaccination. Replying to another question, he said that the government has made a provision to generate ‘Health ID’ (health identity card) of every citizen and by the first week of December more than 14 crore such identity cards were prepared.

COVID-19 Vaccine Booster Dose for Omicron Variant1

Booster shot of Pfizer COVID vaccine can reduce mortality by up to 90%: Study

  • Third dose of Pfizer COVID vaccine may reduce mortality due to delta variant by up to 90%.
  • The research was published Thursday in The New England Journal of Medicine.

According to a study conducted in Israel, a booster shot or third dose of the Pfizer COVID-19 vaccine can reduce the mortality rate due to the delta version of the SARS-CoV-2 virus by up to 90 percent. The research, published Thursday in The New England Journal of Medicine, included data from participants age 50 or older who had received two doses of the Pfizer vaccine at least five months earlier.

The mortality rate due to COVID-19 in participants who received boosters during the study period (booster group) was compared to participants who did not receive boosters (non-booster group). A total of 843,208 participants met eligibility criteria, of whom 758,118 (90 percent) received a booster during the 54-day study period, according to researchers, including those from Clalit Health Services and Ben-Gurion University of the Negev, Israel.

Death due to COVID-19 occurred in 65 participants (0.16 per 100,000 persons per day) in the booster group and 137 participants (2.98 per 100,000 persons per day) in the non-booster group. The study authors noted, “Participants who received the booster at least five months after the second dose of Pfizer had a 90 percent lower death rate due to COVID-19 than those who did not receive the booster.”

COVID-19 Vaccine Booster Dose for Omicron Variant1

The researchers said, that among participants 65 years of age or older, death from COVID-19 occurred in 60 out of 470,808 participants in the booster group and 123 out of 35,208 participants in the non-booster group. Among those under 65, COVID-19 died in 5 out of 287,310 participants in the booster group and 14 out of 49,882 participants in the non-booster group, they said. According to the researchers, among female participants, 54 out of 400,300 participants in the booster group and 13 out of 47,972 participants in the non-booster group died of COVID-19.

The emergence of the delta version of SARS-CoV-2 and the reduced effectiveness over time of the Pfizer vaccine led to a resurgence of COVID-19 cases in populations that were vaccinated early. On July 30, 2021, Israel’s Ministry of Health approved the use of a third dose of the Pfizer vaccine to combat this resurgence.

Booster dose of Covid-19 vaccine is necessary, even better against many epidemics including Omicron

If it’s been six months since you got your second vaccine for the COVID vaccine, it’s time to think about getting your booster vaccine. This will provide additional protection against COVID, including the new Omicron version.

While the evidence is still coming in, preliminary data suggests that the Pfizer booster may provide the same protection against Omicron as double-dose vaccination against the original virus.

Why get a booster?

When you receive the first dose of the COVID vaccine, your body produces an immune response against a part of the virus called the spike protein. In such a situation, if you are exposed to the SARS-CoV-2 virus, your immune system can quickly recognize the virus and fight it. The immune response to a single dose of COVID vaccine is usually short-lived. So a second dose is required for a stronger and longer lasting response. Over time, the amount of antibodies in your body decreases – this is known as weakened immunity.

If the immune response falls below the level required to protect against COVID, your immune system is no longer able to prevent infection when exposed to the virus. A dose of vaccine given sometime after the initial course helps elevate antibody levels above the protective limit.

How long after taking the second dose does immunity decrease?

Antibodies tend to decrease over a period of six months or more after taking the second dose of the Covid vaccine. Six months after completing vaccination, the effectiveness of the vaccine against COVID infection decreases by an average of 18.5 percent. One positive is the fact that the protection against serious illness from COVID, including hospitalization or death, seems to have declined by only about 8 percent during this period, not to that level.

This is possible because other components of the immune response (T cells and immune memory cells) stay in the body longer than antibodies and prevent serious disease. Loss of protection is a concern among the elderly and those with weakened immunity because they have a weaker immune response to vaccines than younger, healthier people.

How effective are booster doses?

Antibody levels after a booster dose are higher than after the initial vaccination. Although the protection against the original virus that caused Covid infection after two doses of the vaccine was slightly lower than against the delta version, a booster vaccine restores the same level of protection.

In Israel, people who received a booster vaccine (five or more months after completing vaccination) had an infection rate ten times lower than those who took the initial two doses. From a safety point of view, the type and frequency of side effects after the booster dose remained the same as for the first and second doses.

COVID-19 Vaccine Booster Dose for Omicron Variant1
Omicron variant 2

Which vaccine should I get as my booster dose?

Two mRNA COVID vaccines available in Australia – Pfizer and Moderna – are now approved for use as booster doses. A recent clinical trial shows that several COVID vaccines, of which all three are currently available in Australia (Pfizer, Moderna and AstraZeneca), and the Novavax and Janssen vaccines, induce stronger immune responses after a course of Pfizer or AstraZeneca vaccines. We do.

Based on what we know so far about immune responses to COVID vaccines, any of these vaccines as a booster should be effective in reducing your risk of infection, regardless of which vaccine you initially received Ho. Highest immune responses were seen with mRNA vaccines, but it is too early to tell whether these provide better protection against COVID infection when used as boosters, or how immune responses are compared to other vaccines. Will end soon.

When is the best time to take my booster dose?

The booster dose is able to increase your antibody levels until they fall below their protective limit. The difficulty with COVID is that we don’t yet know what the protective immunity threshold is. However, this given time also includes other factors such as the extent of disease in the community and the availability of vaccines. Some countries, such as the United Kingdom, recommend a booster dose only three months after the completion of the initial two vaccine courses.

However, this short duration may mean that the increase in the immune response is not as high or as long-lasting. The longer interval between the first and second doses of the Covid vaccine is more effective. Given that the COVID virus is much lower in Australia than in other countries and vaccine coverage is generally high, a booster dose six months after the initial vaccination seems reasonable.

Will Booster protect me from Omicron?

Preliminary laboratory studies suggest that two doses of the Pfizer vaccine confer some immunity against Omicron, but not as much as against previous versions. This means that we are likely to see more infections in fully vaccinated people.

However a booster dose improves immune response in fully vaccinated people to levels similar to those seen against previous versions, and is expected to provide good protection against serious disease. It is, however, a relief to know that preliminary figures indicate this version of the virus to be less severe than the previous one.

(Saira Patel, Australian National University, Jean Lee-Kim-Moy, University of Sydney and Robert Boye, University of Sydney)

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